2025, Vol. 13 Issue 1, Part B
Essential phytoconstituents and bioactive potentials of Helicteres isora in natural product research
AUTHOR(S): Siti Mariam Binti Rahman
ABSTRACT:Helicteres isora L. (Malvaceae), known popularly as the Indian screw tree, has gained increasing scientific attention due to its wide range of ethnomedicinal applications and rich secondary metabolite profile. Traditionally employed in the management of diarrhea, dysentery, diabetes, wounds, and respiratory ailments, the plant has been a component of classical Ayurvedic and folk medicine for centuries. Recent research indicates that its fruits, roots, bark, and stems harbor phenolics, flavonoids, tannins, triterpenoids, phytosterols, neolignans, and cucurbitacins that contribute to multiple biological activities. Antioxidant, antidiabetic, antimicrobial, anti-inflammatory, analgesic, cytoprotective, and hepato-renal protective properties have been reported across in vitro and in vivo models. Despite such promising results, there remains a gap in comprehensive standardization, isolation of bioactive compounds, and clinical evaluation. This paper reviews essential phytochemical classes of H. isora, critically evaluates its reported pharmacological activities, and highlights the safety profile and future potential of the species as a natural product resource.
Pages: 117-119 | 187 Views 34 Downloads
How to cite this article:
Siti Mariam Binti Rahman. Essential phytoconstituents and bioactive potentials of Helicteres isora in natural product research. Am J Essent Oil Nat Prod 2025;13(1):117-119.
