American Journal of Essential Oils and Natural Products
2021, Vol. 9 Issue 3, Part A
Essential oils from Sphaeranthus senegalensis DC accelerate excision wound healing
AUTHOR(S): Obi Peter Adigwe, Bulus Adzu, Christiana Yetunde Isimi, Jemilat Aliyu Ibrahim, Samuel Ehiabhi Okhale and Aliyu Usman
ABSTRACT:Sphaeranthus senegalensis DC is an aromatic annual herb that grows after the season in damp and swampy areas of tropical Africa and Asia. The plant is used for various medicinal uses that include sedative, anti-inflammatory, anti-nociceptive, antidiarrhoeal and gastroprotective. This study focuses on the essential oils from the plant with the aim of evaluating its possible therapeutic usefulness. The fresh plant material was obtained and subjected to hydrodistillation and solvent extraction methods. The chemical constituents of the oils obtained were identified using GC-MS techniques. Hydrocarbons were prevalent, totalling 53.77% in the oil obtained through hydrodistillation and 80.95% for the oil obtained through solvent extraction. Oxygenated constituents constituted 43.76% and 19.15%, respectively. The oil obtained through solvent extraction was tested for acute dermal toxicity and wound-healing effect in rats. Data obtained showed that the oil is safe on the skin and exhibited wound healing activity.
Pages: 14-21 | 625 Views 108 Downloads
How to cite this article:
Obi Peter Adigwe, Bulus Adzu, Christiana Yetunde Isimi, Jemilat Aliyu Ibrahim, Samuel Ehiabhi Okhale, Aliyu Usman. Essential oils from Sphaeranthus senegalensis DC accelerate excision wound healing. Am J Essent Oil Nat Prod 2021;9(3):14-21.