2020, Vol. 8 Issue 4, Part A
Potent free-radical-scavenging activity of bark of Poranopsis paniculata (roxb.) Roberly
AUTHOR(S): Sumnath Khanal, Devi Prasad Bhandari, Laxman Bhandari and Achyut Adhikari
ABSTRACT:In this study, we evaluated the total phenolic content, total flavonoid content, and antioxidant activity of ethanolic extract of bark of Poranopsis paniculata for the first time. The ethanolic extract of P. paniculata was phytochemically screened, total phenolic content (TPC) was determined by Folin-Ciocalteu’s reagent method, total flavonoid content (TFC) was determined by aluminum chloride assay and antioxidant activity was determined by using 1,1-diphenyl-2-picrylhydrazyl assay (DPPH assay). Phytochemical screening revealed the presence of alkaloids, flavonoids, phenolics, carbohydrates, reducing sugars, terpenoids, steroids, tannins. The total phenolic content and flavonoid content are found to be 152.75±2.48 mgGAE/g and 25.7±2.09 mgQE/g respectively. The antioxidant activity of P. paniculata extract was expressed in terms of IC50 values. Interestingly, ethanolic bark extract of P. paniculata showed the very good antioxidant activity with IC50 value 13.57 µg/mL, nearly equal to that of standard ascorbic acid (IC50 = 11.35 µg/mL). Therefore, P. paniculata bark has a significant amount of vital phytoconstituents and strong antioxidant properties.
Pages: 39-42 | 179 Views 8 Downloads
How to cite this article:
Sumnath Khanal, Devi Prasad Bhandari, Laxman Bhandari, Achyut Adhikari. Potent free-radical-scavenging activity of bark of Poranopsis paniculata (roxb.) Roberly. Am J Essent Oil Nat Prod 2020;8(4):39-42.