2020, Vol. 8 Issue 4, Part A
Chemical constituents and antifungal properties of the essential oils from the stem bark of Mitragyna ciliata Aubrév. & Pellegr. and leaves of Cynometra vogelii Hook. f. from Nigeria
AUTHOR(S): Moses S Owolabi, Lanre Akintayo Ogundajo, Balogun Olaoye Solomon, Logunleko Olatunde, Ambika Poudel, Chelsea N Powers and William N Setzer
ABSTRACT:In this study, documentation on the essential oils extracted from the stem bark of Mitragyna ciliata and leaf of Cynometra vogelii were chemically characterized and quantified using GC-MS. The major components in the stem bark of M. ciliata were found to be non-terpenoid derivatives: benzaldehyde (28.3%), hexanal (4.0%), along with monoterpenoids: furanoid (cis-linalool oxide (12.4%) and trans-linalool oxide (7.9%)), 2,5-dimethyl-p-cymene (4.4%), and the fatty acid: palmitic acid (12.5%), while the leaf oil of C. vogelii was dominant with sesquiterpene hydrocarbons: β-caryophyllene (28.6%), α- and β-selinene (11.3% and 9.4%), and the fatty acid ester: isopropyl palmitate (19.2%). The oil of M. ciliata displayed marginal antifungal activity against Aspergillus niger (MIC = 625 µg/mL) and Cryptococcus neoformans (MIC = 313 µg/mL) but no antifungal activity against Candida albicans. Leaf essential oil of C. vogelii displayed good antifungal activity against C. neoformans (MIC = 80 µg/mL) but no antifungal activity against A. niger or C. albicans. The synergistic combination of essential oil constituents and the recent trends in the use of these oils obtained from aromatic plants as antifungals well as their biocidal activities can facilitate their application to overcome the problem of multidrug-resistant micro-organisms in our society.
Pages: 01-05 | 1362 Views 335 Downloads
How to cite this article:
Moses S Owolabi, Lanre Akintayo Ogundajo, Balogun Olaoye Solomon, Logunleko Olatunde, Ambika Poudel, Chelsea N Powers, William N Setzer. Chemical constituents and antifungal properties of the essential oils from the stem bark of Mitragyna ciliata Aubrév. & Pellegr. and leaves of Cynometra vogelii Hook. f. from Nigeria. Am J Essent Oil Nat Prod 2020;8(4):01-05.
