2017, Vol. 5 Issue 4, Part A
Chemical compositions and antimicrobial activity of essential oil from the rhizomes of Curcuma singularis growing in Vietnam
AUTHOR(S): Nguyen Manh Cuong, Vu Thi Ha, Pham Ngoc Khanh, Doan Thi Van, To Dao Cuong, Tran Thu Huong, Dinh Thi Thu Thuy, Ngu Truong Nhan, Nguyen Phuong Hanh, Tran Quoc Toan, Nguyen Quyet Chien, Nguyen Thanh Tung and Nguyen Quoc Binh
ABSTRACT:Curcuma singularis Gagnep., (Zingiberaceae) was found distributed in the Central Highlands of Vietnam and described as a new record for the country’s flora. From the fresh rhizomes of this plant, an essential oil was obtained by hydrodistillation with 0.31% yield (w/w). By GC-FID and GC-MS analysis, a total of 68 compounds were detected, of which 60 components accounting for 90.96% of the total oil were identified. Almost all of the components are mono- and sesquiterpenes (65 compounds, 98.57% total oil), most of them are oxygenated (51 compounds, 85.46% total oil). Major components are camphor (25.83%), germacrone (8.00%), caryophyllene oxide (4.48%), terpinen-4-ol (3.84%), and germacrone-4,5-epoxide (3.84%). In the antibacterial assays, the oil exhibited significant activity against the Gram positive bacteria Bacillus subtillis (MIC = 100 µg/ml) and the Gram negative bacteria Escherichia coli (MIC = 200 µg/ml).
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How to cite this article:
Nguyen Manh Cuong, Vu Thi Ha, Pham Ngoc Khanh, Doan Thi Van, To Dao Cuong, Tran Thu Huong, Dinh Thi Thu Thuy, Ngu Truong Nhan, Nguyen Phuong Hanh, Tran Quoc Toan, Nguyen Quyet Chien, Nguyen Thanh Tung, Nguyen Quoc Binh. Chemical compositions and antimicrobial activity of essential oil from the rhizomes of Curcuma singularis growing in Vietnam. Am J Essent Oil Nat Prod 2017;5(4):20-25.