2017, Vol. 5 Issue 4, Part A
Chemical composition and biological activity of Centella asiatica essential oil from Nepal
AUTHOR(S): Prajwal Paudel, Prabodh Satyal, Noura S Dosoky and William N Setzer
ABSTRACT:The essential oil from the aerial parts of Centella asiatica, collected from Kirtipur, Nepal, was obtained by hydrodistillation and analyzed by gas chromatography – mass spectrometry (GC-MS). The essential oil was dominated by sesquiterpene hydrocarbons, including (E)-β-farnesene (26.5%), α-humulene (20.9%), and (E)-caryophyllene (13.3%). The essential oil was screened for in-vitro cytotoxic activity against MCF-7 cells and antimicrobial activity against Bacillus cereus, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Aspergillus niger. The C. asiatica essential oil showed no antimicrobial activity and was only marginally cytotoxic to MCF-7 cells.
Pages: 05-08 | 1240 Views 100 Downloads
How to cite this article:
Prajwal Paudel, Prabodh Satyal, Noura S Dosoky, William N Setzer. Chemical composition and biological activity of Centella asiatica essential oil from Nepal. Am J Essent Oil Nat Prod 2017;5(4):05-08.