2015, Vol. 3 Issue 1, Part A
Leaf essential oil composition, antimicrobial and cytotoxic activities of Cleistocalyx operculatus from Hetauda, Nepal
AUTHOR(S): Noura S. Dosoky, Suraj K. Pokharel, William N. Setzer
ABSTRACT:The present study investigated the chemical composition and bioactivity of the leaf essential oil from Cleistocalyx operculatus (Roxb.) Merr. & L.M. Perry from Nepal. In this work, leaf essential oil of C. operculatus was obtained by hydrodistillation and analyzed by GC-MS. The major component of the leaf oil was myrcene (69.7%), followed by (E)-β-ocimene (12.24%), (Z)-β-ocimene (4.79%), and linalool (4.08%), with other minor constituents. Antimicrobial activities were determined using the microbroth dilution technique, and in-vitro cytotoxic activity against MCF-7, MDA-MB-231 and 5637 cells was tested using the MTT assay. C. operculatus oil has shown no antimicrobial or cytotoxic activity.
Pages: 34-37 | 1665 Views 18 Downloads
How to cite this article:
Noura S. Dosoky, Suraj K. Pokharel, William N. Setzer. Leaf essential oil composition, antimicrobial and cytotoxic activities of Cleistocalyx operculatus from Hetauda, Nepal. Am J Essent Oil Nat Prod 2015;3(1):34-37.