2015, Vol. 2 Issue 3, Part A
Composition and bioactivities of the leaf essential oil of Ficus religiosa Linn.
AUTHOR(S): Ambika Poudel, Prabodh Satyal, William N. Setzer
ABSTRACT:The leaf essential oil of Ficus religiosa from Nepal was obtained by hydrodistillation and analyzed by gas chromatography – mass spectrometry. The major components of the leaf oil were eugenol (27.0%), itaconic anhydride (15.4%), 3-methyl-cyclopenetane-1, 2-dione (10.8%), 2-phenylethyl alcohol (8.0%), and benzyl alcohol (4.2%). The leaf oil was screened for antimicrobial activity and was marginally active (MIC = 625 μg/mL) against Aspergillus niger, but was inactive (MIC = 2500 μg/mL) against Pseudomonas aeruginosa, Bacillus cereus, Staphylococcus aureus, Escherichia coli, and Candida albicans. The oil was marginally active in the brine shrimp lethality test (LC50 = 50 μg/mL) and also showed in-vitro cytotoxic activity against MCF-7 human breast tumor cell line (80±5% kill at 100 mg/mL).
Pages: 16-17 | 1291 Views 15 Downloads
How to cite this article:
Ambika Poudel, Prabodh Satyal, William N. Setzer. Composition and bioactivities of the leaf essential oil of Ficus religiosa Linn.. Am J Essent Oil Nat Prod 2015;2(3):16-17.