2013, Vol. 1 Issue 1, Part A
Chemical composition, antimicrobial, and cytotoxic assessment of Mitracarpus scaber Zucc. (Rubiaceae) essential oil from southwestern Nigeria
AUTHOR(S): Moses S. Owolabi, Oladipupo A. Lawal, Noura S. Dosoky, Prabodh Satyal, and William N. Setzer
ABSTRACT:The leaf essential oil composition of Mitracarpus scaber was determined by GC-MS. The oil was dominated by pentadecanal (38.5%), methyl (7Z, 10Z, 13Z)-hexadecatrienoate (11.8%), 2, 3-dimethylnaphthoquinone (6.0%), and α-pinene (5.4%). The oil was screened for antimicrobial activity using the broth dilution technique and screened for in-vitro cytotoxic activity against human MCF-7 breast tumor cells. M. scaber leaf oil showed only marginal antibacterial activity against Bacillus cereus (MIC = 625 μg/mL), marginal antifungal activity against Aspergillus niger (MIC = 313 μg/mL), and marginal cytotoxic activity on MCF-7 cells (58.7±7.6% kill at 100 μg/mL).
Pages: 04-06 | 3074 Views 425 Downloads
How to cite this article:
Moses S. Owolabi, Oladipupo A. Lawal, Noura S. Dosoky, Prabodh Satyal,, William N. Setzer. Chemical composition, antimicrobial, and cytotoxic assessment of Mitracarpus scaber Zucc. (Rubiaceae) essential oil from southwestern Nigeria. Am J Essent Oil Nat Prod 2013;1(1):04-06.
