American Journal of Essential Oils and Natural Products
2013, Vol. 1 Issue 1, Part A
The cytotoxic activity of Annona muricata leaf oil from Badagary, Nigeria
AUTHOR(S): Moses S. Owolabi, Akintayo Lanre Ogundajo, Noura S. Dosoky, and William N. Setzer
ABSTRACT:The leaf essential oil of Annona muricata, collected from Badagary, Nigeria, was obtained by hydrodistillation and analyzed by gas chromatography – mass spectrometry. The leaf oil was dominated by (E)-caryophyllene (38.9%) and eugenol (30.2%), with lesser amounts of α-humulene (4.3%), δ-cadinene (6.0%), and caryophyllene oxide (5.0%). A. muricata leaf oil showed notable in-vitro cytotoxic activity on MCF-7 cells (99.2% kill at 100 μg/mL), which can be attributed to the major components.
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How to cite this article:
Moses S. Owolabi, Akintayo Lanre Ogundajo, Noura S. Dosoky,, William N. Setzer. The cytotoxic activity of Annona muricata leaf oil from Badagary, Nigeria. Am J Essent Oil Nat Prod 2013;1(1):01-03.