Volume 4, Issue 1

The floral essential oil composition and biological activity of Solanum macranthum Dunal

Author(s): Emmanuel E Essien, Tameka M Walker, Jennifer M Newby, Isiaka A Ogunwande, William N Setzer, Olusegun Ekundayo

Abstract: The essential oil from the floral part of Solanum macranthum Dunal was obtained by hydrodistillation and analyzed by gas chromatography-mass spectrometry (GC-MS). A total of seventeen compounds were identified representing 100% of the oil composition. Major components of the volatile oil were pentadecane (58.6%), (E)-nerolidol (15.4%), a-phellandrene (7.5%) and (E)-nerolidol acetate (5.6%). The essential oil exhibited strong antimicrobial activity (39-625 μg/ml) on pathogens employed in the assay. However, no appreciable cytotoxic effects on human breast carcinoma cells (Hs 578T) and human prostate carcinoma cells (PC-3) were observed. The floral volatile oil contents of S. macranthum and biological activity is being reported for the first time.

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