2017, Vol. 5 Issue 2, Part A
Comparative studies on In-vitro radical scavenging potential of methanol extracts of Garcinia kola heck (Clusiaceae) seeds, Conyza sumatrensis retz (Asteraceae) and Mitracarpus scaber zucc (Rubiaceae) leaves
AUTHOR(S): Adebayo Muritala Ayofe, Adedokun Oluwasegun, Ayinde Bunyaminu Adesina and Ume Ogochukwu
Dating back to history, widespread use of plants as natural herbal remedies has remained a thing of consideration. In this research, the comparative study on antioxidants or free radical scavenging properties of the methanol extracts of Garcinia kola nut seeds, Conyza sumatrensis and Mitracarpus scaber leaves were evaluated in a series of radical (ROS) scavenging assays involving total antioxidants studies using 1,1-diphenyl 2- picrylhydrazyl (DPPH) radical, reducing power assay, total phenolic and flavonoid contents. However, phytochemical screening of the extracts showed the presence of flavonoids, terpenoids, alkaloids, glycosides and reducing sugars. The lowest and highest amount of phenolic compounds were observed in G. kola (0.31 ± 0.52 mg∕g) and M. scaber (0.48 ± 0.15 mg∕g), which in turn exhibited the greatest amount of flavonoid (0.32 ± 0.15 mg∕g). The extracts of all the examined plants, exhibited a marked antioxidants scavenging effects at the various concentration ranging from 20 - 100 µg/ml using Vitamin C as the reference drug. M. scaber exhibited the highest radical scavenging potential in a concentration dependent manner relative to Vitamin C while C. sumatrensis exhibited the least activity among the examined samples. Similar activities were observed in reducing power assay with all plants exhibiting a low activity relative to Vitamin C (standard drug) at P ≤0.05. In conclusion, findings of this research experimentally justify the ethnopharmacological claim of the usage of M. scaber in treatment of oxidative stress induced ailment.
Pages: 33-36 | 963 Views 29 Downloads
How to cite this article:
Adebayo Muritala Ayofe, Adedokun Oluwasegun, Ayinde Bunyaminu Adesina and Ume Ogochukwu. Comparative studies on In-vitro radical scavenging potential of methanol extracts of Garcinia kola heck (Clusiaceae) seeds, Conyza sumatrensis retz (Asteraceae) and Mitracarpus scaber zucc (Rubiaceae) leaves. American Journal of Essential Oils and Natural Products. 2017; 5(2): 33-36.