2016, Vol. 4 Issue 1, Part A
Essential oil constituents, anticancer and antimicrobial activity of Ficus mucoso and Casuarina equisetifolia leaves
AUTHOR(S): Emmanuel E Essien, Jennifer M Newby, Tameka M Walker, Isiaka A Ogunwande, William N Setzer, Olusegun Ekundayo
ABSTRACT:Essential oils were obtained by hydrodistillation of Ficus mucoso Welw. and Casuarina equisetifolia L. leaves and analyzed for their constituents by means of gas chromatography-mass spectrometry (GC-MS). The major volatile components of F. mucoso leaves were a-phellandrene (13.0%), p-cymene (11.3%), germacrene D (10.5%), b-caryophyllene (9.7%), 1, 8-cineole (9.5%) and a-copaene (8.7%). High levels of a-phellandrene (40.6%), p-cymene (15.7%), 1, 8-cineole (14.1%) and terpinolene (8.4%) characterized C. equisetifolia oil. Ficus mucoso oil demonstrated strong inhibitory activity against Hs578T human breast tumor cells (98.18%) relative to PC-3 human prostate carcinoma cells (47.17%); F. mucoso and C. equisetifolia essential oils also exhibited significant antimicrobial activity (39-625 μg/mL) on pathogens employed in the assays.
Pages: 01-06 | 1154 Views 49 Downloads
How to cite this article:
Emmanuel E Essien, Jennifer M Newby, Tameka M Walker, Isiaka A Ogunwande, William N Setzer, Olusegun Ekundayo. Essential oil constituents, anticancer and antimicrobial activity of Ficus mucoso and Casuarina equisetifolia leaves. American Journal of Essential Oils and Natural Products. 2016; 4(1): 01-06.