American Journal of Essential Oils and Natural Products
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ISSN: 2321-9114, ICV 2016: 79.57

American Journal of Essential Oils and Natural Products

2013, Vol. 1 Issue 1, Part A

Chemical composition, antimicrobial, and cytotoxic assessment of Mitracarpus scaber Zucc. (Rubiaceae) essential oil from southwestern Nigeria

AUTHOR(S): Moses S. Owolabi, Oladipupo A. Lawal, Noura S. Dosoky, Prabodh Satyal, and William N. Setzer
ABSTRACT:The leaf essential oil composition of Mitracarpus scaber was determined by GC-MS. The oil was dominated by pentadecanal (38.5%), methyl (7Z, 10Z, 13Z)-hexadecatrienoate (11.8%), 2, 3-dimethylnaphthoquinone (6.0%), and α-pinene (5.4%). The oil was screened for antimicrobial activity using the broth dilution technique and screened for in-vitro cytotoxic activity against human MCF-7 breast tumor cells. M. scaber leaf oil showed only marginal antibacterial activity against Bacillus cereus (MIC = 625 μg/mL), marginal antifungal activity against Aspergillus niger (MIC = 313 μg/mL), and marginal cytotoxic activity on MCF-7 cells (58.7±7.6% kill at 100 μg/mL).
Pages: 04-06  |  650 Views  13 Downloads
How to cite this article:
Moses S. Owolabi, Oladipupo A. Lawal, Noura S. Dosoky, Prabodh Satyal, and William N. Setzer. Chemical composition, antimicrobial, and cytotoxic assessment of Mitracarpus scaber Zucc. (Rubiaceae) essential oil from southwestern Nigeria. 2013; 1(1): 04-06.
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